相互作用
Aztreonam + Cefpirome
重症度: 軽度
Aztreonam and Cefpirome: minor interaction.
最終更新日
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概要
Aztreonam and cefpirome are both beta-lactam antibiotics with activity against gram-negative bacteria, and the combination can show additive or synergistic killing of some Enterobacteriaceae in vitro. This is generally a therapeutic benefit rather than a harmful interaction, though both drugs can cause hypersensitivity reactions and cross-reactivity is possible with cephalosporins with similar side chains.
この相互作用をわかりやすく説明すると
Aztreonam and Cefpirome have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Aztreonam belongs to Anti Bacterial; Cefpirome belongs to Anti Bacterial.
なぜ起こるのか
Additive pharmacodynamic effect through binding of different penicillin-binding proteins in gram-negative bacteria.
対処法
No routine adjustment is needed; use only when the combined spectrum is clinically intended and guided by culture results. Monitor for hypersensitivity reactions.
薬剤師に尋ねること
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AztreonamとCefpiromeの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Aztreonamのその他の相互作用
Cefpiromeのその他の相互作用
よくある質問
Can I take Aztreonam with Cefpirome?
MediHelp rates the interaction as minor. Aztreonam and Cefpirome have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Aztreonam and cefpirome are both beta-lactam antibiotics with activity against gram-negative bacteria, and the combination can show additive or synergistic killing of some Enterobacteriaceae in vitro. This is generally a therapeutic benefit rather than a harmful interaction, though both drugs can cause hypersensitivity reactions and cross-reactivity is possible with cephalosporins with similar side chains.
How serious is the interaction between Aztreonam and Cefpirome?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed; use only when the combined spectrum is clinically intended and guided by culture results. Monitor for hypersensitivity reactions.
What other medicines interact with Aztreonam?
MediHelp also lists interactions of Aztreonam with, for example, Cefoxitin, Cholera vaccine, Microbiota. The full list is on the Aztreonam page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
