医薬品リファレンス
Cefoperazone
Cefoperazone is a medicine in the class anti bacterial. It is used for endometritis.
- 薬効分類: Anti Bacterial
- 効能・効果: endometritis
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
要点
- 薬効分類
- Anti Bacterial
- 一般的な剤形
- 注射剤
- 一般的な規格
- 1 g, 500 mg, 2 g
- 商品名
- 22
- 国・市場
- 2
何に使われるか
作用のしくみ
Cefoperazone, a third-generation cephalosporin, interferes with cell wall synthesis by binding to the penicillin-binding proteins (PBPs), thus preventing cross-linking of nascent peptidoglycan. Cefoperazone is stable to penicillinases and has a high degree of stability to many beta-lactamases produced by gram-negative bacteria.
成人の通常用量（添付文書の要約）
1 to 2 g IV or IM every 12 hours. Therapy should be continued for 7, 14, 21, or 30 days, according to the type of infection
妊娠と授乳
- 妊娠
- Safe No clear harm in available data; cephalosporins as a class are considered safe in pregnancy. It can lower vitamin K-dependent clotting and cause a reaction with alcohol. Use when needed, with clotting checks if at risk.
- 授乳
- Safe Low milk levels in small studies (often undetectable). LactMed: acceptable; watch the infant for loose stools or thrush.
報告されている副作用
- Diarrhea
- Transient elevations of the BUN
- neutropenia
注意が必要な方
- cefoperazone should be prescribed with caution in individuals with a history of gastrointestinal disease, particularly colitis.
- As with other antibacterial drugs, vitamin K deficiency resulting in coagulopathy has occurred in patients treated with cefoperazone.
- A false-positive reaction for glucose in the urine may occur with Benedict’s or Fehling’s solution.
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Cefoperazoneの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Patient counselling points
- Food interactions
- IV preparation and dilution
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同じ分類のほかの薬剤
よくある質問
What is Cefoperazone used for?
Cefoperazone is a medicine in the class anti bacterial. It is used for Endometritis, Peritonitis, Pyelonephritis, Respiratory tract infections, Skin infections.
What side effects have been reported with Cefoperazone?
Diarrhea, Transient elevations of the BUN, neutropenia.
Can Cefoperazone be taken in pregnancy or while breastfeeding?
Pregnancy: Safe. No clear harm in available data; cephalosporins as a class are considered safe in pregnancy. It can lower vitamin K-dependent clotting and cause a reaction with alcohol. Use when needed, with clotting checks if at risk. Breastfeeding: Safe. Low milk levels in small studies (often undetectable). LactMed: acceptable; watch the infant for loose stools or thrush.
What does Cefoperazone interact with?
MediHelp does not list a checked interaction for Cefoperazone yet. Always tell your pharmacist about every medicine you take.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
