医薬品リファレンス
Darbepoetin alfa
Darbepoetin alfa is a medicine in the class miscellaneous. It is used for anemia.
- 薬効分類: Miscellaneous
- 効能・効果: anemia
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
要点
- 薬効分類
- Miscellaneous
- ATCコード
- B03XA02
- 一般的な剤形
- 注射剤
- 一般的な規格
- 10 mcg, 20 mcg, 30 mcg
- 商品名
- 36
- 国・市場
- 5
何に使われるか
作用のしくみ
Recombinant human erythropoietin with sialic acid additions to enhance stability; stimulates erythropoiesis via division & differentation of progenitor cells in bone marrow to induce the release of reticulocytes from the bone marrow into the bloodstream to become erythrocytes.
成人の通常用量（添付文書の要約）
Chronic Kidney Disease-Associated Anemia: Recommended starting dose: 0.45 mcg/kg IV/SC q4weeks
妊娠と授乳
- 妊娠
- Unknown Limited human data are insufficient to assess risk. In animals it increased early pregnancy loss at doses near the usual starting doses. Weigh the benefit to the mother (e.g. anaemia of kidney disease) against possible fetal risk; use only if needed.
- 授乳
- Safe No milk data. It behaves like natural erythropoietin, which is normally present in milk, and as a large protein it is poorly absorbed by the infant; newborns have been given far larger doses directly. No special precautions are needed.
報告されている副作用
- Headache
- Fatigue
- Diarrhea
- Dizziness
- Edema
- Arthralgia
注意が必要な方
- Hypertensive encephalopathy and seizures reported in patients with CKD
- Decrease dose if Hgb increase exceeds 1 g/dL in any 2 wk period
- If severe anemia and low reticulocyte count develop during treatment, withhold therapy and evaluate for pure red cell aplasia
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Darbepoetin alfaの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- Patient counselling points
- Food interactions
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同じ分類のほかの薬剤
よくある質問
What is Darbepoetin alfa used for?
Darbepoetin alfa is a medicine in the class miscellaneous. It is used for Anemia.
What side effects have been reported with Darbepoetin alfa?
Headache, Fatigue, Diarrhea, Dizziness, Edema, Arthralgia.
Can Darbepoetin alfa be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Limited human data are insufficient to assess risk. In animals it increased early pregnancy loss at doses near the usual starting doses. Weigh the benefit to the mother (e.g. anaemia of kidney disease) against possible fetal risk; use only if needed. Breastfeeding: Safe. No milk data. It behaves like natural erythropoietin, which is normally present in milk, and as a large protein it is poorly absorbed by the infant; newborns have been given far larger doses directly. No special precautions are needed.
What does Darbepoetin alfa interact with?
MediHelp does not list a checked interaction for Darbepoetin alfa yet. Always tell your pharmacist about every medicine you take.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
