医薬品リファレンス
Eflapegrastim
Eflapegrastim is a medicine in the class miscellaneous. It is used for febrile neutropenia.
- 薬効分類: Miscellaneous
- 効能・効果: febrile neutropenia
最終更新日 出典: US FDA label
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
要点
- 薬効分類
- Miscellaneous
- 一般的な剤形
- 注射剤
- 一般的な規格
- 13.2 mg/.6 ml
- 商品名
- 1
- 国・市場
- 1
何に使われるか
作用のしくみ
Recombinant human granulocyte growth factor that binds G-CSF receptors on myeloid progenitor cells and neutrophils, triggering signaling that controls differentiation, proliferation, migration and survival.
成人の通常用量（添付文書の要約）
Decrease incidence of febrile neutropenia in non-myeloid malignancies on myelosuppressive chemotherapy: 13.2 mg, subcutaneous, once per chemotherapy cycle, approximately 24 hours after cytotoxic chemotherapy; do not give from 14 days before to 24 hours after chemotherapy
妊娠と授乳
- 妊娠
- Unknown No human data on Rolvedon; other rhG-CSF products showed no identified drug-associated risk in published studies. In rabbits, embryofetal lethality and reduced fetal weight occurred at approximately 6 times clinical exposure.
- 授乳
- Unknown No data on presence in human milk; other rhG-CSF products are present at low levels. Consider breastfeeding benefits along with maternal clinical need.
報告されている副作用
- Fatigue
- Nausea
- Diarrhea
- Bone pain
- Headache
- Pyrexia
禁忌
- History of serious allergic reactions to eflapegrastim, pegfilgrastim, or filgrastim products (may include anaphylaxis).
注意が必要な方
- Splenic rupture, including fatal cases; evaluate for enlarged spleen if left upper abdominal or shoulder pain.
- ARDS: evaluate patients with fever, lung infiltrates or respiratory distress; discontinue if ARDS.
- Serious allergic reactions including anaphylaxis: permanently discontinue.
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Eflapegrastimの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- How to give it
- Pharmacokinetics
- Patient counselling points
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同じ分類のほかの薬剤
よくある質問
What is Eflapegrastim used for?
Eflapegrastim is a medicine in the class miscellaneous. It is used for Febrile neutropenia.
What side effects have been reported with Eflapegrastim?
Fatigue, Nausea, Diarrhea, Bone pain, Headache, Pyrexia.
Can Eflapegrastim be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. No human data on Rolvedon; other rhG-CSF products showed no identified drug-associated risk in published studies. In rabbits, embryofetal lethality and reduced fetal weight occurred at approximately 6 times clinical exposure. Breastfeeding: Unknown. No data on presence in human milk; other rhG-CSF products are present at low levels. Consider breastfeeding benefits along with maternal clinical need.
What does Eflapegrastim interact with?
MediHelp does not list a checked interaction for Eflapegrastim yet. Always tell your pharmacist about every medicine you take.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
