医薬品リファレンス
Famciclovir
Famciclovir is a medicine in the class anti virals. It is used for genital herpes.
- 薬効分類: Anti Virals
- 効能・効果: genital herpes
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
要点
- 薬効分類
- Anti Virals
- 一般的な剤形
- 錠剤
- 一般的な規格
- 250 mg, 500 mg, 125 mg
- 既知の相互作用
- 10 (重大: 3 · 中等度: 1 · 軽度: 6)
- 商品名
- 17
- 国・市場
- 3
何に使われるか
作用のしくみ
Prodrug of penciclovir, which selectively inhibits viral DNA replication in herpes simplex virus (HSV) type 1 (HSV-1), HSV-2, and varicella zoster virus (VZV)
成人の通常用量（添付文書の要約）
Acute Herpes Zoster (Shingles): 500 mg PO q8hr for 7 days; initiated within 72 hours of symptom or lesion onset
妊娠と授乳
- 妊娠
- Unknown Pharmacovigilance data have not shown a risk of birth defects or miscarriage, and animal studies showed no harm, but human data are limited. Aciclovir or valaciclovir, with far more pregnancy data, are preferred for herpes in pregnancy.
- 授乳
- Unknown No human milk data; in rats milk levels were up to 8 times blood levels. US label: weigh benefits. LactMed: with no published experience, other agents such as aciclovir or valaciclovir may be preferred, especially with a newborn.
報告されている副作用
- Headache
- Diarrhea
- Nausea
- Abdominal pain
- Flatulence
- Dysmenorrhea
禁忌
- Known hypersensitivity to this drug or its active metabolite, penciclovir
主な相互作用 (10)
- Famciclovir + Talimogene laherparepvec Major
- Famciclovir + Varicella virus vaccine live Major
- Famciclovir + Zoster vaccine live Major
- Famciclovir + Tenofovir df Moderate
- Cimetidine + Famciclovir Minor
- Digoxin + Famciclovir Minor
- Famciclovir + Probenecid Minor
- Famciclovir + Raloxifene Minor
- Famciclovir + Tenofovir disoproxil Minor
- Famciclovir + Ublituximab Minor
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Famciclovirの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Pharmacokinetics
- Patient counselling points
- Food interactions
WebでPro+を14日間無料でお試し。カード登録不要。
同じ分類のほかの薬剤
よくある質問
What is Famciclovir used for?
Famciclovir is a medicine in the class anti virals. It is used for Genital herpes, Herpes simplex, Herpes zoster.
What side effects have been reported with Famciclovir?
Headache, Diarrhea, Nausea, Abdominal pain, Flatulence, Dysmenorrhea.
Can Famciclovir be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Pharmacovigilance data have not shown a risk of birth defects or miscarriage, and animal studies showed no harm, but human data are limited. Aciclovir or valaciclovir, with far more pregnancy data, are preferred for herpes in pregnancy. Breastfeeding: Unknown. No human milk data; in rats milk levels were up to 8 times blood levels. US label: weigh benefits. LactMed: with no published experience, other agents such as aciclovir or valaciclovir may be preferred, especially with a newborn.
What does Famciclovir interact with?
MediHelp lists 10 known interactions for Famciclovir. Major: 3 · Moderate: 1 · Minor: 6. The most serious include Talimogene laherparepvec, Varicella virus vaccine live, Zoster vaccine live.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
