相互作用
Famciclovir + Probenecid
重症度: 軽度
Famciclovir and Probenecid: minor interaction.
最終更新日
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概要
Probenecid reduces the renal secretion of penciclovir, the active metabolite of famciclovir, increasing its plasma levels. The change is usually modest and rarely requires action.
この相互作用をわかりやすく説明すると
Famciclovir and Probenecid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Famciclovir belongs to Anti Virals; Probenecid belongs to Genitourinary.
なぜ起こるのか
Probenecid inhibits renal tubular organic anion transport, reducing penciclovir elimination.
対処法
No routine dose adjustment is needed. Monitor for adverse effects such as headache or nausea, and in renal impairment consider dose reduction per labeling.
薬剤師に尋ねること
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、FamciclovirとProbenecidの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Probenecidのその他の相互作用
Famciclovirのその他の相互作用
よくある質問
Can I take Famciclovir with Probenecid?
MediHelp rates the interaction as minor. Famciclovir and Probenecid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Probenecid reduces the renal secretion of penciclovir, the active metabolite of famciclovir, increasing its plasma levels. The change is usually modest and rarely requires action.
How serious is the interaction between Famciclovir and Probenecid?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine dose adjustment is needed. Monitor for adverse effects such as headache or nausea, and in renal impairment consider dose reduction per labeling.
What other medicines interact with Probenecid?
MediHelp also lists interactions of Probenecid with, for example, Ketorolac intranasal, Ketorolac, Baricitinib. The full list is on the Probenecid page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
