医薬品リファレンス
Miltefosine
Miltefosine is a medicine in the class anti parasitic. It is used for leishmaniasis.
- 薬効分類: Anti Parasitic
- 効能・効果: leishmaniasis
最終更新日 出典: US FDA label
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
要点
- 薬効分類
- Anti Parasitic
- 一般的な剤形
- カプセル剤
- 一般的な規格
- 50 mg
- 商品名
- 2
- 国・市場
- 1
何に使われるか
作用のしくみ
Miltefosine is an anti-leishmanial agent.
成人の通常用量（添付文書の要約）
Visceral, cutaneous and mucosal leishmaniasis, weight 30 kg to 44 kg: one 50 mg capsule orally twice daily with food (breakfast and dinner) for 28 consecutive days
妊娠と授乳
- 妊娠
- Unsafe Contraindicated; may cause fetal harm with embryo-fetal toxicity and teratogenicity in animals. Pregnancy test required before prescribing.
- 授乳
- Unsafe Not known if present in human milk; breastfeeding should be avoided during therapy and for 5 months after.
報告されている副作用
- Vomiting
- Nausea
- Diarrhea
- Decreased appetite
- Headache
- Dizziness
警告（枠囲み警告）
- Embryo-fetal toxicity: may cause fetal harm; fetal death and teratogenicity occurred in animals at doses lower than the recommended human dose. Do not give to pregnant women. Obtain a serum or urine pregnancy test in females of reproductive potential before prescribing. Advise effective contraception during therapy and for 5 months after therapy.
禁忌
- Pregnancy
- Sjögren-Larsson-Syndrome
- Hypersensitivity to miltefosine or any of its excipients
注意が必要な方
- Reproductive effects: testicular atrophy and impaired fertility in male rats and impaired fertility in female rats; effects on human fertility not adequately evaluated.
- Renal effects: serum creatinine elevations; monitor renal function weekly during therapy and for 4 weeks after.
- Hepatic effects: monitor ALT, AST and bilirubin during therapy.
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
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アカウントを作成してPro+トライアルを始めると、Miltefosineの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- How to give it
- Pharmacokinetics
- Patient counselling points
- Food interactions
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同じ分類のほかの薬剤
よくある質問
What is Miltefosine used for?
Miltefosine is a medicine in the class anti parasitic. It is used for Leishmaniasis.
What side effects have been reported with Miltefosine?
Vomiting, Nausea, Diarrhea, Decreased appetite, Headache, Dizziness. Serious warning: Embryo-fetal toxicity: may cause fetal harm; fetal death and teratogenicity occurred in animals at doses lower than the recommended human dose.
Can Miltefosine be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. Contraindicated; may cause fetal harm with embryo-fetal toxicity and teratogenicity in animals. Pregnancy test required before prescribing. Breastfeeding: Unsafe. Not known if present in human milk; breastfeeding should be avoided during therapy and for 5 months after.
What does Miltefosine interact with?
MediHelp does not list a checked interaction for Miltefosine yet. Always tell your pharmacist about every medicine you take.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
