医薬品リファレンス
Revakinagene taroretcel
Revakinagene taroretcel is a medicine in the class miscellaneous.
- 薬効分類: Miscellaneous
最終更新日 出典: US FDA label
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
要点
- 薬効分類
- Miscellaneous
- 商品名
- 1
- 国・市場
- 1
作用のしくみ
The implant secretes recombinant human ciliary neurotrophic factor (rhCNTF). Exogenous CNTF is thought to target Müller glia and trigger signaling that may promote photoreceptor survival. The mechanism is not completely understood.
成人の通常用量（添付文書の要約）
Idiopathic macular telangiectasia type 2: one implant per affected eye (200,000 to 440,000 allogeneic RPE cells expressing rhCNTF), single surgical intravitreal implantation by a qualified ophthalmologist
妊娠と授乳
- 妊娠
- Unknown An eye implant of cells releasing ciliary neurotrophic factor (CNTF); no data in pregnant women, and not known if it raises CNTF above natural levels. CNTF under the skin caused no birth defects in rats or rabbits, but fewer implantations and live fetuses in rabbits. Use only if clearly needed.
- 授乳
- Unknown No data on milk or infant effects; no LactMed record. Systemic exposure from the eye implant is not known to rise above natural CNTF levels. US label: weigh benefits of breastfeeding against the mother's need.
報告されている副作用
- Conjunctival hemorrhage
- Delayed dark adaptation
- Foreign body sensation
- Eye pain
- Suture related complications
- Miosis
禁忌
- Active or suspected ocular or periocular infections
- Known hypersensitivity to Endothelial Serum Free Media (Endo-SFM)
注意が必要な方
- Severe vision loss (3 or more lines, ≥15 ETDRS letters) has occurred; monitor patients
- Infectious endophthalmitis may occur; use aseptic technique, monitor, and remove the implant if it occurs
- Retinal tears and detachment may occur; monitor and treat promptly; remove implant if vitrectomy with complete gas or silicone oil fill is required
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
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- Pharmacokinetics
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同じ分類のほかの薬剤
よくある質問
What is Revakinagene taroretcel used for?
Revakinagene taroretcel is a medicine in the class miscellaneous.
What side effects have been reported with Revakinagene taroretcel?
Conjunctival hemorrhage, Delayed dark adaptation, Foreign body sensation, Eye pain, Suture related complications, Miosis.
Can Revakinagene taroretcel be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. An eye implant of cells releasing ciliary neurotrophic factor (CNTF); no data in pregnant women, and not known if it raises CNTF above natural levels. CNTF under the skin caused no birth defects in rats or rabbits, but fewer implantations and live fetuses in rabbits. Use only if clearly needed. Breastfeeding: Unknown. No data on milk or infant effects; no LactMed record. Systemic exposure from the eye implant is not known to rise above natural CNTF levels. US label: weigh benefits of breastfeeding against the mother's need.
What does Revakinagene taroretcel interact with?
MediHelp does not list a checked interaction for Revakinagene taroretcel yet. Always tell your pharmacist about every medicine you take.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
