医薬品リファレンス
Strontium ranelate
Strontium ranelate is a medicine in the class musculoskeletal. It is used for osteoporosis.
- 薬効分類: Musculoskeletal
- 効能・効果: osteoporosis
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
要点
- 薬効分類
- Musculoskeletal
- 一般的な剤形
- 分包
- 一般的な規格
- 2 g
- 既知の相互作用
- 10 (重大: 2 · 中等度: 8)
- 商品名
- 8
- 国・市場
- 2
何に使われるか
作用のしくみ
Some reports have shown that strontium ranelate can slow down the progression of osteoarthritis of the knee. This agent presents an atypical mechanism of action in which it increases deposition of new bone by osteoblasts and, simultaneously, reduces the resorption of bone by osteoclasts.
成人の通常用量（添付文書の要約）
The recommended dose is one 2 g sachet once daily by oral administration.
通常の服用方法
Simple analgesics are taken by mouth, by rectum or by infusion as needed within a daily maximum that counts every product containing the same ingredient.
妊娠と授乳
- 妊娠
- Unknown Only for osteoporosis after menopause (use now restricted; EU marketing stopped). No human data; high doses caused reversible bone effects in rat and rabbit offspring. EU label: if used inadvertently in pregnancy, stop treatment.
- 授乳
- Unknown Not known in humans; physico-chemical data suggest strontium passes into milk. EU label: should not be used while breastfeeding. No LactMed record. Not indicated in women of breastfeeding age; use calcium and vitamin D measures instead.
報告されている副作用
- Headache
- Insomnia
- Hypercholesterolaemia
- Confusion
- Disturbances in consciousness
注意が必要な方
- Contraindicated in Uncontrolled hypertension.
Paracetamol-type analgesics need care in people with liver disease, chronic alcohol use or low body weight, and the daily limit must include every combination product that contains the same ingredient.
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
主な相互作用 (10)
- Minocycline + Strontium ranelate Major
- Strontium ranelate + Tetracycline Major
- Aluminum hydroxide + Strontium ranelate Moderate
- Calcium + Strontium ranelate Moderate
- Calcium carbonate + Strontium ranelate Moderate
- Doxycycline + Strontium ranelate Moderate
- Gemifloxacin + Strontium ranelate Moderate
- Levofloxacin + Strontium ranelate Moderate
- Moxifloxacin + Strontium ranelate Moderate
- Ofloxacin + Strontium ranelate Moderate
Pro+会員向け
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アカウントを作成してPro+トライアルを始めると、Strontium ranelateの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- Patient counselling points
- Food interactions
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よくある質問
What is Strontium ranelate used for?
Strontium ranelate is a medicine in the class musculoskeletal. It is used for Osteoporosis.
What side effects have been reported with Strontium ranelate?
Headache, Insomnia, Hypercholesterolaemia, Confusion, Disturbances in consciousness.
Can Strontium ranelate be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Only for osteoporosis after menopause (use now restricted; EU marketing stopped). No human data; high doses caused reversible bone effects in rat and rabbit offspring. EU label: if used inadvertently in pregnancy, stop treatment. Breastfeeding: Unknown. Not known in humans; physico-chemical data suggest strontium passes into milk. EU label: should not be used while breastfeeding. No LactMed record. Not indicated in women of breastfeeding age; use calcium and vitamin D measures instead.
What does Strontium ranelate interact with?
MediHelp lists 10 known interactions for Strontium ranelate. Major: 2 · Moderate: 8. The most serious include Minocycline, Tetracycline, Aluminum hydroxide.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
