相互作用
Ofloxacin + Strontium ranelate
重症度: 中等度
Ofloxacin and Strontium ranelate: moderate interaction.
最終更新日
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概要
Oral strontium ranelate can bind ofloxacin in the gut and reduce its absorption, which may lead to subtherapeutic antibiotic concentrations and treatment failure. The effect is relevant only when both are taken by mouth.
この相互作用をわかりやすく説明すると
Ofloxacin and Strontium ranelate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ofloxacin belongs to Anti Bacterial; Strontium ranelate belongs to Musculoskeletal.
なぜ起こるのか
Chelation of the fluoroquinolone by divalent strontium cations in the gastrointestinal tract, reducing absorption.
対処法
Interrupt strontium ranelate for the duration of oral ofloxacin therapy. If it cannot be stopped, separate doses widely and watch for clinical response.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、OfloxacinとStrontium ranelateの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Ofloxacinのその他の相互作用
Strontium ranelateのその他の相互作用
よくある質問
Can I take Ofloxacin with Strontium ranelate?
MediHelp rates the interaction as moderate. Ofloxacin and Strontium ranelate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral strontium ranelate can bind ofloxacin in the gut and reduce its absorption, which may lead to subtherapeutic antibiotic concentrations and treatment failure. The effect is relevant only when both are taken by mouth.
How serious is the interaction between Ofloxacin and Strontium ranelate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Interrupt strontium ranelate for the duration of oral ofloxacin therapy. If it cannot be stopped, separate doses widely and watch for clinical response.
What other medicines interact with Ofloxacin?
MediHelp also lists interactions of Ofloxacin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Ofloxacin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
