相互作用
Minocycline + Strontium ranelate
重症度: 重大
Minocycline and Strontium ranelate: major interaction.
最終更新日
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概要
Oral strontium ranelate can bind minocycline in the gut and lower its absorption, risking subtherapeutic antibiotic levels. This applies to oral forms of both drugs.
この相互作用をわかりやすく説明すると
Minocycline and Strontium ranelate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Minocycline belongs to Anti Bacterial; Strontium ranelate belongs to Musculoskeletal.
なぜ起こるのか
Chelation by divalent strontium cations in the gastrointestinal tract reduces minocycline absorption.
対処法
Suspend strontium ranelate during minocycline therapy and restart it after the antibiotic course is complete.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、MinocyclineとStrontium ranelateの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Minocyclineのその他の相互作用
Strontium ranelateのその他の相互作用
よくある質問
Can I take Minocycline with Strontium ranelate?
MediHelp rates the interaction as major. Minocycline and Strontium ranelate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Oral strontium ranelate can bind minocycline in the gut and lower its absorption, risking subtherapeutic antibiotic levels. This applies to oral forms of both drugs.
How serious is the interaction between Minocycline and Strontium ranelate?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Suspend strontium ranelate during minocycline therapy and restart it after the antibiotic course is complete.
What other medicines interact with Minocycline?
MediHelp also lists interactions of Minocycline with, for example, Acitretin, Isotretinoin, Cholera vaccine. The full list is on the Minocycline page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
