医薬品リファレンス
Vecuronium
Vecuronium is a medicine in the class musculoskeletal. It is used for general anesthesia.
- 薬効分類: Musculoskeletal
- 効能・効果: general anesthesia
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
要点
- 薬効分類
- Musculoskeletal
- 一般的な剤形
- 注射剤
- 一般的な規格
- 4 mg/ml
- 既知の相互作用
- 135 (重大: 14 · 中等度: 62 · 軽度: 59)
- 商品名
- 1
- 国・市場
- 1
何に使われるか
作用のしくみ
Non-depolarizing skeletal muscle relaxant; cholinergic receptor antagonist
成人の通常用量（添付文書の要約）
General Anesthesia (Injection) Load: 0.08-0.1 mg/kg IVP over 60 sec OR 0.04-0.06 mg/kg IVP if following succinylcholine, PLUS Maintenance: 0.01-0.015 mg/kg IVP 20-45min post initial PRN
妊娠と授乳
- 妊娠
- Safe Used during general anaesthesia, including caesarean section; it crosses the placenta only in small amounts. No animal reproduction studies. US label: use only if clearly needed. Magnesium sulphate can prolong its effect. Acceptable for anaesthesia when needed.
- 授乳
- Safe No milk data, but it is short acting, highly polar and poorly absorbed by mouth, so little reaches milk or the infant (LactMed). Breastfeed once the mother has recovered; with several anaesthetic drugs, follow the most restrictive one.
報告されている副作用
- Skeletal muscle weakness or paralysis
- Itching
- Respiratory insufficiency or apnea
禁忌
- Hypersensitivity
- Lack of ventilatory support
- Neuromuscular disease
注意が必要な方
- Some patients may experience prolonged recovery (paralysis) of neuromuscular function
- CAUTION: Hepatobiliary obstruction, renal dysfunction will significantly prolong duration of action
- Severe anaphylactic reactions to neuromuscular blocking agents have been reported; these reactions have, in some cases, been life threatening and fatal;
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
主な相互作用 (135)
- Amikacin + Vecuronium Major
- Bacitracin-neomycin-polymyxin + Vecuronium Major
- Capreomycin + Vecuronium Major
- Clindamycin + Vecuronium Major
- Colistin + Vecuronium Major
- Dexamethasone-tobramycin + Vecuronium Major
- Gentamicin + Vecuronium Major
- Lincomycin + Vecuronium Major
- Magnesium + Vecuronium Major
- Magnesium sulfate + Vecuronium Major
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Vecuroniumの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- Pharmacokinetics
- Patient counselling points
- Food interactions
- IV preparation and dilution
WebでPro+を7日間無料でお試し。カード登録不要。
同じ分類のほかの薬剤
よくある質問
What is Vecuronium used for?
Vecuronium is a medicine in the class musculoskeletal. It is used for General anesthesia.
What side effects have been reported with Vecuronium?
Skeletal muscle weakness or paralysis, Itching, Respiratory insufficiency or apnea.
Can Vecuronium be taken in pregnancy or while breastfeeding?
Pregnancy: Safe. Used during general anaesthesia, including caesarean section; it crosses the placenta only in small amounts. No animal reproduction studies. US label: use only if clearly needed. Magnesium sulphate can prolong its effect. Acceptable for anaesthesia when needed. Breastfeeding: Safe. No milk data, but it is short acting, highly polar and poorly absorbed by mouth, so little reaches milk or the infant (LactMed). Breastfeed once the mother has recovered; with several anaesthetic drugs, follow the most restrictive one.
What does Vecuronium interact with?
MediHelp lists 135 known interactions for Vecuronium. Major: 14 · Moderate: 62 · Minor: 59. The most serious include Amikacin, Bacitracin-neomycin-polymyxin, Capreomycin.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
