相互作用
Aclidinium + Atropine
重症度: 中等度
Aclidinium and Atropine: moderate interaction.
最終更新日
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概要
Both are antimuscarinic agents, so using them together adds to anticholinergic effects. Patients may develop dry mouth, constipation, urinary retention, tachycardia, blurred vision or raised intraocular pressure.
この相互作用をわかりやすく説明すると
Aclidinium and Atropine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
なぜ起こるのか
Additive muscarinic receptor antagonism.
対処法
Avoid routine concurrent use of inhaled aclidinium with other antimuscarinics where possible. Monitor for urinary retention, glaucoma symptoms and constipation, and stop one agent if anticholinergic toxicity appears.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AclidiniumとAtropineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Atropineのその他の相互作用
よくある質問
Can I take Aclidinium with Atropine?
MediHelp rates the interaction as moderate. Aclidinium and Atropine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both are antimuscarinic agents, so using them together adds to anticholinergic effects. Patients may develop dry mouth, constipation, urinary retention, tachycardia, blurred vision or raised intraocular pressure.
How serious is the interaction between Aclidinium and Atropine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid routine concurrent use of inhaled aclidinium with other antimuscarinics where possible. Monitor for urinary retention, glaucoma symptoms and constipation, and stop one agent if anticholinergic toxicity appears.
What other medicines interact with Atropine?
MediHelp also lists interactions of Atropine with, for example, Eluxadoline, Henbane, Pramlintide. The full list is on the Atropine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
