相互作用
Amantadine + Atropine
重症度: 中等度
Amantadine and Atropine: moderate interaction.
最終更新日
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概要
Amantadine has anticholinergic properties, and atropine is a potent antimuscarinic. Together they may increase dry mouth, blurred vision, constipation, urinary retention, tachycardia and confusion, particularly in older adults.
この相互作用をわかりやすく説明すると
Amantadine and Atropine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amantadine belongs to Anti Virals; Atropine belongs to Miscellaneous.
なぜ起こるのか
Additive anticholinergic effects (pharmacodynamic).
対処法
Monitor for anticholinergic effects and mental status changes, especially in elderly patients. Reduce the dose of one agent if adverse effects develop.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AmantadineとAtropineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Amantadineのその他の相互作用
Atropineのその他の相互作用
よくある質問
Can I take Amantadine with Atropine?
MediHelp rates the interaction as moderate. Amantadine and Atropine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Amantadine has anticholinergic properties, and atropine is a potent antimuscarinic. Together they may increase dry mouth, blurred vision, constipation, urinary retention, tachycardia and confusion, particularly in older adults.
How serious is the interaction between Amantadine and Atropine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic effects and mental status changes, especially in elderly patients. Reduce the dose of one agent if adverse effects develop.
What other medicines interact with Amantadine?
MediHelp also lists interactions of Amantadine with, for example, Ethanol, Memantine-donepezil, Metoclopramide. The full list is on the Amantadine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
