相互作用
Atropine + Henbane
重症度: 重大
Atropine and Henbane: major interaction.
最終更新日
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概要
Henbane contains hyoscyamine and scopolamine, which are antimuscarinic alkaloids, so use with atropine gives duplicate anticholinergic effects. Toxicity may present as dry mouth, tachycardia, hyperthermia, confusion and hallucinations.
この相互作用をわかりやすく説明すると
Atropine and Henbane can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
なぜ起こるのか
Additive muscarinic receptor antagonism from the tropane alkaloid content.
対処法
Avoid the combination, as henbane has variable alkaloid content. If anticholinergic toxicity develops, stop both and give supportive care.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AtropineとHenbaneの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Atropineのその他の相互作用
よくある質問
Can I take Atropine with Henbane?
MediHelp rates the interaction as major. Atropine and Henbane can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Henbane contains hyoscyamine and scopolamine, which are antimuscarinic alkaloids, so use with atropine gives duplicate anticholinergic effects. Toxicity may present as dry mouth, tachycardia, hyperthermia, confusion and hallucinations.
How serious is the interaction between Atropine and Henbane?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination, as henbane has variable alkaloid content. If anticholinergic toxicity develops, stop both and give supportive care.
What other medicines interact with Atropine?
MediHelp also lists interactions of Atropine with, for example, Eluxadoline, Pramlintide, Abobotulinumtoxina. The full list is on the Atropine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
