相互作用
Aldesleukin + Guanfacine
重症度: 中等度
Aldesleukin and Guanfacine: moderate interaction.
最終更新日
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概要
Aldesleukin commonly produces hypotension, and guanfacine lowers blood pressure and heart rate through central alpha-2 agonism. Combined use may cause excessive hypotension and sedation.
この相互作用をわかりやすく説明すると
Aldesleukin and Guanfacine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aldesleukin belongs to Oncology; Guanfacine belongs to Cardiovascular.
なぜ起こるのか
Additive hypotensive effects.
対処法
Consider holding guanfacine around aldesleukin cycles and monitor blood pressure and heart rate. Avoid abrupt long-term discontinuation to prevent rebound hypertension.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AldesleukinとGuanfacineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Aldesleukinのその他の相互作用
Guanfacineのその他の相互作用
よくある質問
Can I take Aldesleukin with Guanfacine?
MediHelp rates the interaction as moderate. Aldesleukin and Guanfacine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Aldesleukin commonly produces hypotension, and guanfacine lowers blood pressure and heart rate through central alpha-2 agonism. Combined use may cause excessive hypotension and sedation.
How serious is the interaction between Aldesleukin and Guanfacine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Consider holding guanfacine around aldesleukin cycles and monitor blood pressure and heart rate. Avoid abrupt long-term discontinuation to prevent rebound hypertension.
What other medicines interact with Aldesleukin?
MediHelp also lists interactions of Aldesleukin with, for example, Alfuzosin, Amifostine, Amlodipine-benazepril. The full list is on the Aldesleukin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
