相互作用
Almotriptan + Ergotamine
重症度: 併用禁忌
Almotriptan and Ergotamine: contraindicated interaction.
最終更新日
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概要
Ergotamine and almotriptan both constrict vascular smooth muscle through serotonin receptors. Used in close succession they can cause sustained vasospasm with cerebral or limb ischaemia.
この相互作用をわかりやすく説明すると
Almotriptan and Ergotamine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Almotriptan belongs to Central Nervous System; Ergotamine belongs to Central Nervous System.
なぜ起こるのか
Additive vasoconstriction (5-HT1B/1D agonism)
対処法
Separate the two by at least 24 hours or choose a single agent.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
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アカウントを作成してPro+トライアルを始めると、AlmotriptanとErgotamineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Almotriptanのその他の相互作用
Ergotamineのその他の相互作用
よくある質問
Can I take Almotriptan with Ergotamine?
MediHelp rates the interaction as contraindicated. Almotriptan and Ergotamine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ergotamine and almotriptan both constrict vascular smooth muscle through serotonin receptors. Used in close succession they can cause sustained vasospasm with cerebral or limb ischaemia.
How serious is the interaction between Almotriptan and Ergotamine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate the two by at least 24 hours or choose a single agent.
What other medicines interact with Almotriptan?
MediHelp also lists interactions of Almotriptan with, for example, Dihydroergotamine, Dihydroergotamine intranasal, Eletriptan. The full list is on the Almotriptan page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
