医薬品リファレンス
Ergotamine
Ergotamine is a medicine in the class central nervous system. It is used for migraine.
- 薬効分類: Central Nervous System
- 効能・効果: migraine
最終更新日
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要点
- 薬効分類
- Central Nervous System
- 一般的な剤形
- 錠剤
- 一般的な規格
- 2 mg
- 既知の相互作用
- 270 (併用禁忌: 41 · 重大: 81 · 中等度: 98 · 軽度: 50)
- 商品名
- 1
- 国・市場
- 1
何に使われるか
作用のしくみ
Stimulates alpha receptors to vasoconstrict vessels with low vascular tone; vasodilates hypertonic vessels; at higher doses competes for alpha receptor to block it
成人の通常用量（添付文書の要約）
Migraine: 2 mg SL followed by 1-2 mg q30min until attack abated; not to exceed 6 mg/day and no more than 10 mg/week OR
妊娠と授乳
- 妊娠
- Unsafe Contraindicated in pregnancy: it stimulates the uterus and constricts uterine blood vessels, risking miscarriage and reduced fetal blood flow and growth. Use other migraine treatments.
- 授乳
- Unsafe Passes into milk and may cause vomiting, diarrhoea, weak pulse and unstable blood pressure in the infant; it may also lower milk supply. Most authorities consider it contraindicated while breastfeeding.
報告されている副作用
- Angina
- Abnormal heart valve findings
- Arrhythmia
- Vascular spasm
- Vasoconstriction
注意が必要な方
- Ergotism is manifested by intense arterial vasoconstriction, producing signs and symptoms of peripheral vascular ischemia
- If the condition is allowed to progress untreated, gangrene can result; while most cases of ergotism associated with ergotamine treatment result from frank overdosage
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
主な相互作用 (270)
- Almotriptan + Ergotamine Contraindicated
- Atazanavir + Ergotamine Contraindicated
- Clarithromycin + Ergotamine Contraindicated
- Cobicistat + Ergotamine Contraindicated
- Darunavir + Ergotamine Contraindicated
- Dihydroergotamine + Ergotamine Contraindicated
- Dihydroergotamine intranasal + Ergotamine Contraindicated
- Duvelisib + Ergotamine Contraindicated
- Eletriptan + Ergotamine Contraindicated
- Elvitegravir / cobicistat / emtricitabine / tenofovir df + Ergotamine Contraindicated
Pro+会員向け
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アカウントを作成してPro+トライアルを始めると、Ergotamineの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- Dosing in older adults
- Patient counselling points
- Food interactions
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同じ分類のほかの薬剤
よくある質問
What is Ergotamine used for?
Ergotamine is a medicine in the class central nervous system. It is used for Migraine.
What side effects have been reported with Ergotamine?
Angina, Abnormal heart valve findings, Arrhythmia, Vascular spasm, Vasoconstriction.
Can Ergotamine be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. Contraindicated in pregnancy: it stimulates the uterus and constricts uterine blood vessels, risking miscarriage and reduced fetal blood flow and growth. Use other migraine treatments. Breastfeeding: Unsafe. Passes into milk and may cause vomiting, diarrhoea, weak pulse and unstable blood pressure in the infant; it may also lower milk supply. Most authorities consider it contraindicated while breastfeeding.
What does Ergotamine interact with?
MediHelp lists 270 known interactions for Ergotamine. Contraindicated: 41 · Major: 81 · Moderate: 98 · Minor: 50. The most serious include Almotriptan, Atazanavir, Clarithromycin.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
