相互作用
Alprazolam + Lasmiditan
重症度: 中等度
Alprazolam and Lasmiditan: moderate interaction.
最終更新日
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概要
Lasmiditan commonly causes dizziness and sedation, and alprazolam is a sedating benzodiazepine. Taken together they may produce additive drowsiness and impaired psychomotor and cognitive performance. This combination has not been formally studied.
この相互作用をわかりやすく説明すると
Alprazolam and Lasmiditan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Alprazolam belongs to Central Nervous System; Lasmiditan belongs to Central Nervous System.
なぜ起こるのか
Additive central nervous system depression through pharmacodynamic synergism.
対処法
Counsel the patient to avoid driving or operating machinery for at least 8 hours after each lasmiditan dose. Monitor for excessive sedation and reduce doses if it occurs.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AlprazolamとLasmiditanの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Alprazolamのその他の相互作用
Lasmiditanのその他の相互作用
よくある質問
Can I take Alprazolam with Lasmiditan?
MediHelp rates the interaction as moderate. Alprazolam and Lasmiditan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lasmiditan commonly causes dizziness and sedation, and alprazolam is a sedating benzodiazepine. Taken together they may produce additive drowsiness and impaired psychomotor and cognitive performance. This combination has not been formally studied.
How serious is the interaction between Alprazolam and Lasmiditan?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel the patient to avoid driving or operating machinery for at least 8 hours after each lasmiditan dose. Monitor for excessive sedation and reduce doses if it occurs.
What other medicines interact with Alprazolam?
MediHelp also lists interactions of Alprazolam with, for example, Calcium / magnesium / potassium / sodium oxybates, Itraconazole, Ketoconazole. The full list is on the Alprazolam page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
