医薬品リファレンス

Lasmiditan

Lasmiditan is a medicine in the class central nervous system. It is used for migraine.

薬効分類: Central Nervous System
効能・効果: migraine

最終更新日 15 10月 2026 出典: US FDA label

医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。

このページの臨床コンテンツは英語でのみ提供されています。

要点

薬効分類: Central Nervous System
ATCコード: N02CC08
一般的な剤形: 錠剤
一般的な規格: 100 mg
既知の相互作用: 220 (中等度: 159 · 軽度: 61)
商品名: 3
国・市場: 3

剤形、規格、商品名は国によって異なります。お手元の製品をご確認ください。

何に使われるか

Migraine

作用のしくみ

Binds with high affinity to the 5-HT1F receptor and presumably acts through agonist effects at this receptor; the precise mechanism is unknown.

成人の通常用量（添付文書の要約）

Acute treatment of migraine with or without aura: 50 mg, 100 mg, or 200 mg orally as needed; no more than one dose in 24 hours

添付文書の最初の用法・用量の行のみの要約です。用法・用量の全項目はアプリでご覧いただけます。

妊娠と授乳

妊娠: Unsafe No adequate human data. In animals it caused fetal abnormalities, fetal and pup deaths and lower fetal weight, in rabbits at exposures below human levels. EU label: not recommended in pregnancy. Prefer a better-studied migraine drug (e.g. sumatriptan); a pregnancy registry exists.
授乳: Unknown No human milk data; rat milk levels were about 3 times plasma. US label: weigh benefits. EU label: decide; avoiding breastfeeding for 24 hours after a dose minimises exposure. LactMed: not a reason to stop for an older infant, but another drug may be preferred for a newborn or preterm infant.

報告されている副作用

Dizziness
Fatigue
Paresthesia
Sedation
Nausea and/or vomiting
Muscle weakness

注意が必要な方

Driving impairment: do not drive or operate machinery for at least 8 hours after each dose; patients unable to comply should not take it.
CNS depression, including dizziness and sedation; use caution with alcohol or other CNS depressants.
Serotonin syndrome reported; discontinue if suspected.

妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。

主な相互作用 (220)

Alprazolam + Lasmiditan Moderate
Amiodarone + Lasmiditan Moderate
Amisulpride + Lasmiditan Moderate
Amobarbital + Lasmiditan Moderate
Aripiprazole + Lasmiditan Moderate
Asenapine + Lasmiditan Moderate
Atenolol + Lasmiditan Moderate
Atenolol-chlorthalidone + Lasmiditan Moderate
Atorvastatin + Lasmiditan Moderate
Baclofen + Lasmiditan Moderate

All 220 interactions, with severity and what to do

Pro+会員向け

ページ全体を見る

アカウントを作成してPro+トライアルを始めると、Lasmiditanの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。

Dosing by age, kidney and liver function, and further dose lines
Renal and hepatic dose adjustments
Dosing in older adults
How to give it
Pharmacokinetics
Patient counselling points
Food interactions

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WebでPro+を14日間無料でお試し。カード登録不要。

同じ分類のほかの薬剤

よくある質問

What is Lasmiditan used for?

Lasmiditan is a medicine in the class central nervous system. It is used for Migraine.

What side effects have been reported with Lasmiditan?

Dizziness, Fatigue, Paresthesia, Sedation, Nausea and/or vomiting, Muscle weakness.

Can Lasmiditan be taken in pregnancy or while breastfeeding?

Pregnancy: Unsafe. No adequate human data. In animals it caused fetal abnormalities, fetal and pup deaths and lower fetal weight, in rabbits at exposures below human levels. EU label: not recommended in pregnancy. Prefer a better-studied migraine drug (e.g. sumatriptan); a pregnancy registry exists. Breastfeeding: Unknown. No human milk data; rat milk levels were about 3 times plasma. US label: weigh benefits. EU label: decide; avoiding breastfeeding for 24 hours after a dose minimises exposure. LactMed: not a reason to stop for an older infant, but another drug may be preferred for a newborn or preterm infant.

What does Lasmiditan interact with?

MediHelp lists 220 known interactions for Lasmiditan. Moderate: 159 · Minor: 61. The most serious include Alprazolam, Amiodarone, Amisulpride.

完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで

MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。

ダウンロード：App Store 入手：Google Play

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