相互作用
Atenolol-chlorthalidone + Lasmiditan
重症度: 中等度
Atenolol-chlorthalidone and Lasmiditan: moderate interaction.
最終更新日
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概要
Lasmiditan can slow the heart rate, and this effect is additive with beta-blockers such as atenolol. A pharmacokinetic study with propranolol showed an extra decrease in heart rate. The combination is usually tolerable but may cause bradycardia or dizziness.
この相互作用をわかりやすく説明すると
Atenolol-chlorthalidone and Lasmiditan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atenolol-chlorthalidone belongs to Cardiovascular; Lasmiditan belongs to Central Nervous System.
なぜ起こるのか
Additive heart rate lowering through pharmacodynamic synergism.
対処法
Monitor heart rate and symptoms of bradycardia after lasmiditan dosing. Use caution in patients with baseline bradycardia or conduction disease.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
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アカウントを作成してPro+トライアルを始めると、Atenolol-chlorthalidoneとLasmiditanの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Atenolol-chlorthalidoneのその他の相互作用
Lasmiditanのその他の相互作用
よくある質問
Can I take Atenolol-chlorthalidone with Lasmiditan?
MediHelp rates the interaction as moderate. Atenolol-chlorthalidone and Lasmiditan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lasmiditan can slow the heart rate, and this effect is additive with beta-blockers such as atenolol. A pharmacokinetic study with propranolol showed an extra decrease in heart rate. The combination is usually tolerable but may cause bradycardia or dizziness.
How serious is the interaction between Atenolol-chlorthalidone and Lasmiditan?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and symptoms of bradycardia after lasmiditan dosing. Use caution in patients with baseline bradycardia or conduction disease.
What other medicines interact with Atenolol-chlorthalidone?
MediHelp also lists interactions of Atenolol-chlorthalidone with, for example, Acebutolol, Aldesleukin, Amiodarone. The full list is on the Atenolol-chlorthalidone page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
