相互作用
Aluminum hydroxide + Cefuroxime
重症度: 中等度
Aluminum hydroxide and Cefuroxime: moderate interaction.
最終更新日
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概要
Raising gastric pH with antacids lowers the bioavailability of oral cefuroxime axetil. Reduced exposure may cause treatment failure in infections.
この相互作用をわかりやすく説明すると
Aluminum hydroxide and Cefuroxime can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aluminum hydroxide belongs to Gastrointestinal Tract; Cefuroxime belongs to Anti Bacterial.
なぜ起こるのか
Elevated gastric pH reduces dissolution and absorption of cefuroxime axetil.
対処法
Separate cefuroxime axetil from the antacid by at least 2 hours, giving cefuroxime with food. Monitor clinical response if acid-reducing therapy is continuous.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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アカウントを作成してPro+トライアルを始めると、Aluminum hydroxideとCefuroximeの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Aluminum hydroxideのその他の相互作用
Cefuroximeのその他の相互作用
よくある質問
Can I take Aluminum hydroxide with Cefuroxime?
MediHelp rates the interaction as moderate. Aluminum hydroxide and Cefuroxime can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Raising gastric pH with antacids lowers the bioavailability of oral cefuroxime axetil. Reduced exposure may cause treatment failure in infections.
How serious is the interaction between Aluminum hydroxide and Cefuroxime?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate cefuroxime axetil from the antacid by at least 2 hours, giving cefuroxime with food. Monitor clinical response if acid-reducing therapy is continuous.
What other medicines interact with Aluminum hydroxide?
MediHelp also lists interactions of Aluminum hydroxide with, for example, Ciprofloxacin, Deferasirox, Dolutegravir. The full list is on the Aluminum hydroxide page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
