相互作用
Cefuroxime + Cimetidine
重症度: 中等度
Cefuroxime and Cimetidine: moderate interaction.
最終更新日
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概要
Reduced gastric acidity decreases absorption of cefuroxime axetil. This may lead to subtherapeutic antibiotic levels.
この相互作用をわかりやすく説明すると
Cefuroxime and Cimetidine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefuroxime belongs to Anti Bacterial; Cimetidine belongs to Gastrointestinal Tract.
なぜ起こるのか
Higher gastric pH reduces cefuroxime axetil absorption.
対処法
Give cefuroxime axetil with food and monitor clinical response. Consider avoiding acid suppression or choosing another antibiotic.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CefuroximeとCimetidineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Cimetidineのその他の相互作用
Cefuroximeのその他の相互作用
よくある質問
Can I take Cefuroxime with Cimetidine?
MediHelp rates the interaction as moderate. Cefuroxime and Cimetidine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Reduced gastric acidity decreases absorption of cefuroxime axetil. This may lead to subtherapeutic antibiotic levels.
How serious is the interaction between Cefuroxime and Cimetidine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give cefuroxime axetil with food and monitor clinical response. Consider avoiding acid suppression or choosing another antibiotic.
What other medicines interact with Cimetidine?
MediHelp also lists interactions of Cimetidine with, for example, Dofetilide, Fezolinetant, Alfentanil. The full list is on the Cimetidine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
