相互作用
Aminolevulinic acid + Tetracycline
重症度: 中等度
Aminolevulinic acid and Tetracycline: moderate interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Oral aminolevulinic acid causes protoporphyrin accumulation and photosensitivity, and tetracyclines are also phototoxic. Using them together may increase the risk of severe phototoxic skin reactions.
この相互作用をわかりやすく説明すると
Aminolevulinic acid and Tetracycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aminolevulinic acid belongs to Miscellaneous; Tetracycline belongs to Anti Bacterial.
なぜ起こるのか
Additive phototoxicity from photosensitizing agents.
対処法
Avoid giving tetracycline during the 24 hours around aminolevulinic acid administration and counsel the patient on strict sun and bright light protection.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Aminolevulinic acidとTetracyclineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Tetracyclineのその他の相互作用
Aminolevulinic acidのその他の相互作用
よくある質問
Can I take Aminolevulinic acid with Tetracycline?
MediHelp rates the interaction as moderate. Aminolevulinic acid and Tetracycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral aminolevulinic acid causes protoporphyrin accumulation and photosensitivity, and tetracyclines are also phototoxic. Using them together may increase the risk of severe phototoxic skin reactions.
How serious is the interaction between Aminolevulinic acid and Tetracycline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid giving tetracycline during the 24 hours around aminolevulinic acid administration and counsel the patient on strict sun and bright light protection.
What other medicines interact with Tetracycline?
MediHelp also lists interactions of Tetracycline with, for example, Acitretin, Methoxyflurane, Isotretinoin. The full list is on the Tetracycline page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
