相互作用
Tetracycline + Tretinoin
重症度: 重大
Tetracycline and Tretinoin: major interaction.
最終更新日
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概要
Both tetracyclines and systemic tretinoin can cause raised intracranial pressure (pseudotumor cerebri). Together the risk of headache, visual disturbance and papilledema may be increased.
この相互作用をわかりやすく説明すると
Tetracycline and Tretinoin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Tetracycline belongs to Anti Bacterial; Tretinoin belongs to Dermatology.
なぜ起こるのか
Additive pharmacodynamic risk of idiopathic intracranial hypertension; exact mechanism not established.
対処法
Avoid combining systemic tretinoin with tetracyclines and use an alternative antibiotic; if unavoidable, monitor for headache and visual symptoms and stop at once if they appear.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、TetracyclineとTretinoinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Tetracyclineのその他の相互作用
Tretinoinのその他の相互作用
よくある質問
Can I take Tetracycline with Tretinoin?
MediHelp rates the interaction as major. Tetracycline and Tretinoin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both tetracyclines and systemic tretinoin can cause raised intracranial pressure (pseudotumor cerebri). Together the risk of headache, visual disturbance and papilledema may be increased.
How serious is the interaction between Tetracycline and Tretinoin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining systemic tretinoin with tetracyclines and use an alternative antibiotic; if unavoidable, monitor for headache and visual symptoms and stop at once if they appear.
What other medicines interact with Tetracycline?
MediHelp also lists interactions of Tetracycline with, for example, Acitretin, Methoxyflurane, Isotretinoin. The full list is on the Tetracycline page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。