相互作用
Amiodarone + Anagrelide
重症度: 重大
Amiodarone and Anagrelide: major interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Both agents can prolong the QT interval and anagrelide may also cause tachyarrhythmias and palpitations. Co-use raises the risk of torsades de pointes.
この相互作用をわかりやすく説明すると
Amiodarone and Anagrelide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Amiodarone belongs to Cardiovascular; Anagrelide belongs to Cardiovascular.
なぜ起こるのか
Additive QT prolongation (pharmacodynamic).
対処法
Avoid if possible. If combined, get a baseline ECG, monitor QTc regularly and correct potassium and magnesium.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AmiodaroneとAnagrelideの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Amiodaroneのその他の相互作用
Anagrelideのその他の相互作用
よくある質問
Can I take Amiodarone with Anagrelide?
MediHelp rates the interaction as major. Amiodarone and Anagrelide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both agents can prolong the QT interval and anagrelide may also cause tachyarrhythmias and palpitations. Co-use raises the risk of torsades de pointes.
How serious is the interaction between Amiodarone and Anagrelide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid if possible. If combined, get a baseline ECG, monitor QTc regularly and correct potassium and magnesium.
What other medicines interact with Amiodarone?
MediHelp also lists interactions of Amiodarone with, for example, Amisulpride, Arsenic trioxide, Dofetilide. The full list is on the Amiodarone page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
