相互作用
Amitriptyline + Azelastine
重症度: 中等度
Amitriptyline and Azelastine: moderate interaction.
最終更新日
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概要
Both drugs have sedative properties, and amitriptyline also has strong anticholinergic effects. Concurrent use may increase drowsiness, dizziness and impaired psychomotor performance.
この相互作用をわかりやすく説明すると
Amitriptyline and Azelastine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amitriptyline belongs to Central Nervous System; Azelastine belongs to Respiratory.
なぜ起こるのか
Additive CNS depression via H1-receptor antagonism from both agents, plus anticholinergic effects of amitriptyline.
対処法
Counsel on additive sedation and avoid driving until tolerance is established. Monitor elderly patients for confusion and falls.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AmitriptylineとAzelastineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Azelastineのその他の相互作用
Amitriptylineのその他の相互作用
よくある質問
Can I take Amitriptyline with Azelastine?
MediHelp rates the interaction as moderate. Amitriptyline and Azelastine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs have sedative properties, and amitriptyline also has strong anticholinergic effects. Concurrent use may increase drowsiness, dizziness and impaired psychomotor performance.
How serious is the interaction between Amitriptyline and Azelastine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel on additive sedation and avoid driving until tolerance is established. Monitor elderly patients for confusion and falls.
What other medicines interact with Azelastine?
MediHelp also lists interactions of Azelastine with, for example, Calcium / magnesium / potassium / sodium oxybates, Methadone, Sodium oxybate. The full list is on the Azelastine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
