相互作用
Amlodipine-perindopril + Protein a column
重症度: 併用禁忌
Amlodipine-perindopril and Protein a column: contraindicated interaction.
最終更新日
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概要
ACE inhibitor-treated patients undergoing protein A immunoadsorption have experienced anaphylactoid reactions, related to bradykinin accumulation.
この相互作用をわかりやすく説明すると
Amlodipine-perindopril and Protein a column are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
ACE inhibition prevents bradykinin breakdown, so bradykinin accumulates during column exposure and triggers anaphylactoid reactions.
対処法
Stop perindopril well before the procedure (about 72 hours per labeling) and use another antihypertensive class meanwhile.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Amlodipine-perindoprilとProtein a columnの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Amlodipine-perindoprilのその他の相互作用
よくある質問
Can I take Amlodipine-perindopril with Protein a column?
MediHelp rates the interaction as contraindicated. Amlodipine-perindopril and Protein a column are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. ACE inhibitor-treated patients undergoing protein A immunoadsorption have experienced anaphylactoid reactions, related to bradykinin accumulation.
How serious is the interaction between Amlodipine-perindopril and Protein a column?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Stop perindopril well before the procedure (about 72 hours per labeling) and use another antihypertensive class meanwhile.
What other medicines interact with Amlodipine-perindopril?
MediHelp also lists interactions of Amlodipine-perindopril with, for example, Aliskiren, Sacubitril / valsartan, Amifostine. The full list is on the Amlodipine-perindopril page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
