相互作用
Amphotericin b + Corticotropin
重症度: 中等度
Amphotericin b and Corticotropin: moderate interaction.
最終更新日
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概要
Both amphotericin B and corticotropin promote potassium loss. Together they can cause severe hypokalemia, which may lead to arrhythmias and muscle weakness, and may be worsened by cardiac glycosides.
この相互作用をわかりやすく説明すると
Amphotericin b and Corticotropin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amphotericin b belongs to Anti Fungals; Corticotropin belongs to Endocrine.
なぜ起こるのか
Additive renal potassium wasting (amphotericin tubular effect plus mineralocorticoid effect of corticotropin).
対処法
Monitor serum potassium and cardiac status, and supplement potassium as needed. Check magnesium too.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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アカウントを作成してPro+トライアルを始めると、Amphotericin bとCorticotropinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Amphotericin bのその他の相互作用
Corticotropinのその他の相互作用
よくある質問
Can I take Amphotericin b with Corticotropin?
MediHelp rates the interaction as moderate. Amphotericin b and Corticotropin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both amphotericin B and corticotropin promote potassium loss. Together they can cause severe hypokalemia, which may lead to arrhythmias and muscle weakness, and may be worsened by cardiac glycosides.
How serious is the interaction between Amphotericin b and Corticotropin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and cardiac status, and supplement potassium as needed. Check magnesium too.
What other medicines interact with Amphotericin b?
MediHelp also lists interactions of Amphotericin b with, for example, Cidofovir, Adefovir, Amikacin. The full list is on the Amphotericin b page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
