相互作用
Anagrelide + Macimorelin
重症度: 重大
Anagrelide and Macimorelin: major interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Macimorelin can prolong the QT interval, and anagrelide may add to this. The combination could raise the risk of ventricular arrhythmia during or after the diagnostic test.
この相互作用をわかりやすく説明すると
Anagrelide and Macimorelin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Anagrelide belongs to Cardiovascular; Macimorelin belongs to Endocrine.
なぜ起こるのか
Additive pharmacodynamic QT prolongation.
対処法
Avoid using macimorelin in patients taking anagrelide, or use another growth hormone deficiency diagnostic test. If unavoidable, hold anagrelide beforehand where feasible and monitor ECG.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AnagrelideとMacimorelinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Anagrelideのその他の相互作用
Macimorelinのその他の相互作用
よくある質問
Can I take Anagrelide with Macimorelin?
MediHelp rates the interaction as major. Anagrelide and Macimorelin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Macimorelin can prolong the QT interval, and anagrelide may add to this. The combination could raise the risk of ventricular arrhythmia during or after the diagnostic test.
How serious is the interaction between Anagrelide and Macimorelin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid using macimorelin in patients taking anagrelide, or use another growth hormone deficiency diagnostic test. If unavoidable, hold anagrelide beforehand where feasible and monitor ECG.
What other medicines interact with Anagrelide?
MediHelp also lists interactions of Anagrelide with, for example, Panobinostat, Pimozide, Thioridazine. The full list is on the Anagrelide page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
