相互作用
Anagrelide + Ofloxacin
重症度: 重大
Anagrelide and Ofloxacin: major interaction.
最終更新日
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概要
Anagrelide can prolong the QT interval and cause tachyarrhythmias, and ofloxacin may add to the QT effect. Together they may increase the risk of serious ventricular arrhythmia.
この相互作用をわかりやすく説明すると
Anagrelide and Ofloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Anagrelide belongs to Cardiovascular; Ofloxacin belongs to Anti Bacterial.
なぜ起こるのか
Additive QT prolongation.
対処法
Avoid the combination when an alternative antibiotic exists. If needed, check baseline ECG and electrolytes and monitor the QTc.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AnagrelideとOfloxacinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Ofloxacinのその他の相互作用
Anagrelideのその他の相互作用
よくある質問
Can I take Anagrelide with Ofloxacin?
MediHelp rates the interaction as major. Anagrelide and Ofloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Anagrelide can prolong the QT interval and cause tachyarrhythmias, and ofloxacin may add to the QT effect. Together they may increase the risk of serious ventricular arrhythmia.
How serious is the interaction between Anagrelide and Ofloxacin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination when an alternative antibiotic exists. If needed, check baseline ECG and electrolytes and monitor the QTc.
What other medicines interact with Ofloxacin?
MediHelp also lists interactions of Ofloxacin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Ofloxacin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
