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相互作用

Antithrombin iii + Vitamin e

重症度: 軽度

Antithrombin iii and Vitamin e: minor interaction.

最終更新日

医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。

このページの臨床コンテンツは英語でのみ提供されています。

概要

Antithrombin III potentiates heparin-mediated anticoagulation, and very high doses of vitamin E may modestly impair clotting. Combined use could theoretically increase bleeding tendency, but this is unlikely at ordinary intakes.

この相互作用をわかりやすく説明すると

Antithrombin iii and Vitamin e have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

エビデンスレベル: Low

なぜ起こるのか

Theoretical additive anticoagulant effect, as high-dose vitamin E antagonizes vitamin K-dependent clotting and inhibits platelets.

対処法

Avoid megadose vitamin E during antithrombin therapy. Monitor for bleeding and coagulation parameters as per routine care.

薬剤師に尋ねること

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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アカウントを作成してPro+トライアルを始めると、Antithrombin iiiとVitamin eの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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よくある質問

Can I take Antithrombin iii with Vitamin e?

MediHelp rates the interaction as minor. Antithrombin iii and Vitamin e have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Antithrombin III potentiates heparin-mediated anticoagulation, and very high doses of vitamin E may modestly impair clotting. Combined use could theoretically increase bleeding tendency, but this is unlikely at ordinary intakes.

How serious is the interaction between Antithrombin iii and Vitamin e?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid megadose vitamin E during antithrombin therapy. Monitor for bleeding and coagulation parameters as per routine care.

What other medicines interact with Vitamin e?

MediHelp also lists interactions of Vitamin e with, for example, Betrixaban, Phenindione, Selumetinib. The full list is on the Vitamin e page.

完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで

MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。

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