相互作用
Artemether + Octreotide
重症度: 重大
Artemether and Octreotide: major interaction.
最終更新日
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概要
Artemether can prolong the QT interval, and octreotide may add to this through bradycardia and repolarization effects. The combination may increase the risk of torsades de pointes.
この相互作用をわかりやすく説明すると
Artemether and Octreotide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
なぜ起こるのか
Additive QTc prolongation.
対処法
Avoid if possible; otherwise perform a baseline and follow-up ECG and correct potassium and magnesium before and during treatment.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、ArtemetherとOctreotideの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Octreotideのその他の相互作用
よくある質問
Can I take Artemether with Octreotide?
MediHelp rates the interaction as major. Artemether and Octreotide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Artemether can prolong the QT interval, and octreotide may add to this through bradycardia and repolarization effects. The combination may increase the risk of torsades de pointes.
How serious is the interaction between Artemether and Octreotide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid if possible; otherwise perform a baseline and follow-up ECG and correct potassium and magnesium before and during treatment.
What other medicines interact with Octreotide?
MediHelp also lists interactions of Octreotide with, for example, Adagrasib, Amisulpride, Arsenic trioxide. The full list is on the Octreotide page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
