相互作用
Asenapine + Dexbrompheniramine
重症度: 中等度
Asenapine and Dexbrompheniramine: moderate interaction.
最終更新日
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概要
Asenapine and this sedating antihistamine can produce additive drowsiness, dizziness and psychomotor impairment. Anticholinergic effects may also be additive.
この相互作用をわかりやすく説明すると
Asenapine and Dexbrompheniramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Asenapine belongs to Central Nervous System; Dexbrompheniramine belongs to Respiratory.
なぜ起こるのか
Additive CNS depression via histamine H1 antagonism from both drugs, with additive antimuscarinic effects.
対処法
Counsel patients about impaired alertness and driving. Consider a non-sedating antihistamine if one is needed long term.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AsenapineとDexbrompheniramineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Asenapineのその他の相互作用
Dexbrompheniramineのその他の相互作用
よくある質問
Can I take Asenapine with Dexbrompheniramine?
MediHelp rates the interaction as moderate. Asenapine and Dexbrompheniramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Asenapine and this sedating antihistamine can produce additive drowsiness, dizziness and psychomotor impairment. Anticholinergic effects may also be additive.
How serious is the interaction between Asenapine and Dexbrompheniramine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients about impaired alertness and driving. Consider a non-sedating antihistamine if one is needed long term.
What other medicines interact with Asenapine?
MediHelp also lists interactions of Asenapine with, for example, Pimozide, Thioridazine, Vandetanib. The full list is on the Asenapine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
