相互作用
Brimonidine + Dexbrompheniramine
重症度: 中等度
Brimonidine and Dexbrompheniramine: moderate interaction.
最終更新日
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概要
Dexbrompheniramine is a sedating first-generation antihistamine. Together with brimonidine, drowsiness and reduced alertness may be increased.
この相互作用をわかりやすく説明すると
Brimonidine and Dexbrompheniramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Brimonidine belongs to Miscellaneous; Dexbrompheniramine belongs to Respiratory.
なぜ起こるのか
Additive CNS depression from central H1 blockade and alpha-2 agonism.
対処法
Advise patients to avoid driving or hazardous tasks if drowsy. Consider a non-sedating antihistamine as an alternative.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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アカウントを作成してPro+トライアルを始めると、BrimonidineとDexbrompheniramineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Brimonidineのその他の相互作用
Dexbrompheniramineのその他の相互作用
よくある質問
Can I take Brimonidine with Dexbrompheniramine?
MediHelp rates the interaction as moderate. Brimonidine and Dexbrompheniramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dexbrompheniramine is a sedating first-generation antihistamine. Together with brimonidine, drowsiness and reduced alertness may be increased.
How serious is the interaction between Brimonidine and Dexbrompheniramine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid driving or hazardous tasks if drowsy. Consider a non-sedating antihistamine as an alternative.
What other medicines interact with Brimonidine?
MediHelp also lists interactions of Brimonidine with, for example, Isocarboxazid, Linezolid, Phenelzine. The full list is on the Brimonidine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。