医薬品リファレンス
Dexbrompheniramine
Dexbrompheniramine is a medicine in the class respiratory. It is used for allergic rhinitis.
- 薬効分類: Respiratory
- 効能・効果: allergic rhinitis
最終更新日 出典: US FDA label
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要点
- 薬効分類
- Respiratory
- 一般的な剤形
- 錠剤
- 一般的な規格
- 2 mg
- 既知の相互作用
- 10 (中等度: 9 · 軽度: 1)
- 商品名
- 1
- 国・市場
- 1
何に使われるか
作用のしくみ
Dexbrompheniramine is the pharmacologically active dextrorotatory (S)-enantiomer of brompheniramine. It is a first-generation alkylamine (propylamine) antihistamine that competitively blocks histamine H1 receptors. This reduces histamine-mediated effects such as increased capillary permeability, vasodilation, itching, sneezing and rhinorrhoea.
成人の通常用量（添付文書の要約）
Hay fever/upper respiratory allergy symptoms (adults and children 12 years and over): 1 tablet (2 mg) orally every 4 to 6 hours; not to exceed 6 tablets in 24 hours
妊娠と授乳
- 妊娠
- Unknown Older antihistamine, mostly in cold and allergy combinations; limited human data with no clear link to birth defects. Loratadine or cetirizine have more pregnancy data and are preferred. Avoid combinations with decongestants in early pregnancy.
- 授乳
- Safe LactMed: small occasional doses are not expected to harm the infant. Larger or prolonged doses may sedate the infant or reduce milk supply, especially with pseudoephedrine. A bedtime dose after the last feed limits exposure.
報告されている副作用
- Drowsiness
- Excitability, especially in children
注意が必要な方
- Ask a doctor before use if you have a breathing problem such as emphysema or chronic bronchitis, glaucoma, or trouble urinating due to an enlarged prostate
- Excitability may occur, especially in children
- May cause drowsiness; use caution when driving or operating machinery
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
主な相互作用 (10)
- Amisulpride + Dexbrompheniramine Moderate
- Asenapine + Dexbrompheniramine Moderate
- Brexpiprazole + Dexbrompheniramine Moderate
- Brimonidine + Dexbrompheniramine Moderate
- Brivaracetam + Dexbrompheniramine Moderate
- Cariprazine + Dexbrompheniramine Moderate
- Dexbrompheniramine + Esketamine Moderate
- Dexbrompheniramine + Fentanyl Moderate
- Dexbrompheniramine + Levetiracetam Moderate
- Dexbrompheniramine + Lurasidone Minor
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Dexbrompheniramineの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- How to give it
- Patient counselling points
- Food interactions
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同じ分類のほかの薬剤
よくある質問
What is Dexbrompheniramine used for?
Dexbrompheniramine is a medicine in the class respiratory. It is used for Allergic rhinitis, Hay fever.
What side effects have been reported with Dexbrompheniramine?
Drowsiness, Excitability, especially in children.
Can Dexbrompheniramine be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Older antihistamine, mostly in cold and allergy combinations; limited human data with no clear link to birth defects. Loratadine or cetirizine have more pregnancy data and are preferred. Avoid combinations with decongestants in early pregnancy. Breastfeeding: Safe. LactMed: small occasional doses are not expected to harm the infant. Larger or prolonged doses may sedate the infant or reduce milk supply, especially with pseudoephedrine. A bedtime dose after the last feed limits exposure.
What does Dexbrompheniramine interact with?
MediHelp lists 10 known interactions for Dexbrompheniramine. Moderate: 9 · Minor: 1. The most serious include Amisulpride, Asenapine, Brexpiprazole.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
