相互作用
Asenapine + Dexchlorpheniramine
重症度: 中等度
Asenapine and Dexchlorpheniramine: moderate interaction.
最終更新日
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概要
Combining asenapine with this sedating antihistamine can cause additive drowsiness and impaired psychomotor performance. Additive anticholinergic effects such as dry mouth and constipation may occur.
この相互作用をわかりやすく説明すると
Asenapine and Dexchlorpheniramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Asenapine belongs to Central Nervous System; Dexchlorpheniramine belongs to Respiratory.
なぜ起こるのか
Additive CNS depression via H1 antagonism from both drugs, with additive antimuscarinic effects.
対処法
Warn patients about sedation and avoid driving until response is known. Prefer a non-sedating antihistamine where possible.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AsenapineとDexchlorpheniramineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Asenapineのその他の相互作用
Dexchlorpheniramineのその他の相互作用
よくある質問
Can I take Asenapine with Dexchlorpheniramine?
MediHelp rates the interaction as moderate. Asenapine and Dexchlorpheniramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Combining asenapine with this sedating antihistamine can cause additive drowsiness and impaired psychomotor performance. Additive anticholinergic effects such as dry mouth and constipation may occur.
How serious is the interaction between Asenapine and Dexchlorpheniramine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Warn patients about sedation and avoid driving until response is known. Prefer a non-sedating antihistamine where possible.
What other medicines interact with Asenapine?
MediHelp also lists interactions of Asenapine with, for example, Pimozide, Thioridazine, Vandetanib. The full list is on the Asenapine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
