相互作用
Atropine iv / + Glycopyrronium
重症度: 中等度
Atropine iv / and Glycopyrronium: moderate interaction.
最終更新日
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概要
Both are antimuscarinics, so their combination adds to anticholinergic effects including tachycardia, dry mouth, urinary retention and reduced gut motility. This is often intentional perioperatively but can lead to excessive effects.
この相互作用をわかりやすく説明すると
Atropine iv / and Glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
なぜ起こるのか
Additive muscarinic receptor blockade.
対処法
Avoid unnecessary duplication; monitor heart rate, and watch for urinary retention, ileus and delirium, particularly in elderly patients.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Atropine iv /とGlycopyrroniumの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Glycopyrroniumのその他の相互作用
よくある質問
Can I take Atropine iv / with Glycopyrronium?
MediHelp rates the interaction as moderate. Atropine iv / and Glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both are antimuscarinics, so their combination adds to anticholinergic effects including tachycardia, dry mouth, urinary retention and reduced gut motility. This is often intentional perioperatively but can lead to excessive effects.
How serious is the interaction between Atropine iv / and Glycopyrronium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid unnecessary duplication; monitor heart rate, and watch for urinary retention, ileus and delirium, particularly in elderly patients.
What other medicines interact with Glycopyrronium?
MediHelp also lists interactions of Glycopyrronium with, for example, Clozapine, Abobotulinumtoxina, Aclidinium. The full list is on the Glycopyrronium page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
