医薬品リファレンス
Glycopyrronium
Glycopyrronium is a medicine in the class respiratory. It is used for copd.
- 薬効分類: Respiratory
- 効能・効果: copd
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
要点
- 薬効分類
- Respiratory
- ATCコード
- R03BB06, A03AB02
- 一般的な剤形
- 吸入器, 注射剤
- 一般的な規格
- 50 mcg, 1 mg/5 ml, 2.4 g/100 g
- 既知の相互作用
- 107 (重大: 1 · 中等度: 88 · 軽度: 18)
- 商品名
- 10
- 国・市場
- 5
何に使われるか
作用のしくみ
Long-acting muscarinic antagonist (LAMA); often referred to as an anticholinergic; produces bronchodilation by inhibiting acetylcholine’s effect on muscarinic receptors in the airway smooth muscle.
成人の通常用量（添付文書の要約）
Surgery (Preoperative): 4mcg/kg IM 30-60 min before surgery. (Intraoperative): 0.1 mg IV; may repeat q2-3min
妊娠と授乳
- 妊娠
- Unknown Injection: very little crosses the placenta; widely used in anaesthesia, including caesarean section, without fetal heart effects. Oral and inhaled forms: no human data; no birth defects in rats or rabbits. Some UK injection labels: not recommended. Use only if clearly needed.
- 授乳
- Safe No milk data; it is poorly absorbed by the infant (quaternary drug). Single doses (e.g. anaesthesia) and inhaled or skin use are unlikely to matter. Long-term oral use may reduce milk supply; watch the infant's weight gain.
報告されている副作用
- Upper respiratory tract infection
- Nasopharyngitis
- Oropharyngeal pain
禁忌
- Hypersensitivity to drug or components
- Glaucoma
- Obstructive uropathies, including prostatic hypertrophyMechanical obstructive diseases of gastrointestinal tract (eg, pyloroduodenalstenosis, strictures)
主な相互作用 (107)
- Clozapine + Glycopyrronium Major
- Abobotulinumtoxina + Glycopyrronium Moderate
- Aclidinium + Glycopyrronium Moderate
- Amantadine + Glycopyrronium Moderate
- Amitriptyline + Glycopyrronium Moderate
- Amoxapine + Glycopyrronium Moderate
- Atropine + Glycopyrronium Moderate
- Atropine iv / + Glycopyrronium Moderate
- Belladonna alkaloids + Glycopyrronium Moderate
- Belladonna and opium + Glycopyrronium Moderate
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Glycopyrroniumの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Pharmacokinetics
- Food interactions
- IV preparation and dilution
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同じ分類のほかの薬剤
よくある質問
What is Glycopyrronium used for?
Glycopyrronium is a medicine in the class respiratory. It is used for COPD.
What side effects have been reported with Glycopyrronium?
Upper respiratory tract infection, Nasopharyngitis, Oropharyngeal pain.
Can Glycopyrronium be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Injection: very little crosses the placenta; widely used in anaesthesia, including caesarean section, without fetal heart effects. Oral and inhaled forms: no human data; no birth defects in rats or rabbits. Some UK injection labels: not recommended. Use only if clearly needed. Breastfeeding: Safe. No milk data; it is poorly absorbed by the infant (quaternary drug). Single doses (e.g. anaesthesia) and inhaled or skin use are unlikely to matter. Long-term oral use may reduce milk supply; watch the infant's weight gain.
What does Glycopyrronium interact with?
MediHelp lists 107 known interactions for Glycopyrronium. Major: 1 · Moderate: 88 · Minor: 18. The most serious include Clozapine, Abobotulinumtoxina, Aclidinium.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
