相互作用
Azelaic acid + Urea
重症度: 軽度
Azelaic acid and Urea: minor interaction.
最終更新日 出典: US FDA label
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概要
Co-application may increase local irritation such as stinging, burning and dryness. Urea can disrupt the stratum corneum and may increase skin penetration of other topical agents. The effect is usually mild and is more likely at higher urea strengths or on damaged skin.
この相互作用をわかりやすく説明すると
Azelaic acid and Urea have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Azelaic acid belongs to Dermatology; Urea belongs to Miscellaneous.
なぜ起こるのか
Additive local irritation, with urea's keratolytic and hydrating action possibly increasing penetration of azelaic acid.
対処法
If both are needed, apply them at different times of day or on alternate days and avoid broken skin. Start with low-strength urea and monitor for irritation.
薬剤師に尋ねること
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Azelaic acidとUreaの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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参考文献
Azelaic acidのその他の相互作用
Ureaのその他の相互作用
よくある質問
Can I take Azelaic acid with Urea?
MediHelp rates the interaction as minor. Azelaic acid and Urea have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Co-application may increase local irritation such as stinging, burning and dryness. Urea can disrupt the stratum corneum and may increase skin penetration of other topical agents. The effect is usually mild and is more likely at higher urea strengths or on damaged skin.
How serious is the interaction between Azelaic acid and Urea?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: If both are needed, apply them at different times of day or on alternate days and avoid broken skin. Start with low-strength urea and monitor for irritation.
What other medicines interact with Azelaic acid?
MediHelp also lists interactions of Azelaic acid with, for example, Tretinoin. The full list is on the Azelaic acid page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
