相互作用
Azelaic acid + Tretinoin
重症度: 軽度
Azelaic acid and Tretinoin: minor interaction.
最終更新日 出典: US FDA label
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このページの臨床コンテンツは英語でのみ提供されています。
概要
Using both topical agents together can cause additive local irritation such as redness, dryness, burning and peeling. The combination is used deliberately in some acne and hyperpigmentation regimens, and irritation is usually manageable. Patients with sensitive skin or rosacea are most affected.
この相互作用をわかりやすく説明すると
Azelaic acid and Tretinoin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Azelaic acid belongs to Dermatology; Tretinoin belongs to Dermatology.
なぜ起こるのか
Pharmacodynamic additive local irritation from tretinoin-induced epidermal turnover and the mild irritant effect of azelaic acid.
対処法
Apply at different times, for example azelaic acid in the morning and tretinoin at night, or alternate days at the start. Begin with low frequency or strength and use a moisturizer.
薬剤師に尋ねること
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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アカウントを作成してPro+トライアルを始めると、Azelaic acidとTretinoinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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参考文献
- Finacea (azelaic acid) Gel Prescribing Information — FDA Label
- Retin-A (tretinoin) Prescribing Information — FDA Label
Azelaic acidのその他の相互作用
Tretinoinのその他の相互作用
よくある質問
Can I take Azelaic acid with Tretinoin?
MediHelp rates the interaction as minor. Azelaic acid and Tretinoin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Using both topical agents together can cause additive local irritation such as redness, dryness, burning and peeling. The combination is used deliberately in some acne and hyperpigmentation regimens, and irritation is usually manageable. Patients with sensitive skin or rosacea are most affected.
How serious is the interaction between Azelaic acid and Tretinoin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Apply at different times, for example azelaic acid in the morning and tretinoin at night, or alternate days at the start. Begin with low frequency or strength and use a moisturizer.
What other medicines interact with Azelaic acid?
MediHelp also lists interactions of Azelaic acid with, for example, Urea. The full list is on the Azelaic acid page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
