相互作用
Baloxavir marboxil + Ferrous sulfate
重症度: 中等度
Baloxavir marboxil and Ferrous sulfate: moderate interaction.
最終更新日
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概要
Baloxavir can bind to polyvalent cations such as iron in the gut, which may lower its absorption and reduce plasma exposure. This could weaken antiviral effect during influenza treatment or prophylaxis. Supporting data come mainly from animal studies.
この相互作用をわかりやすく説明すると
Baloxavir marboxil and Ferrous sulfate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Baloxavir marboxil belongs to Anti Virals; Ferrous sulfate belongs to Miscellaneous.
なぜ起こるのか
Chelation of baloxavir by iron in the gastrointestinal tract reduces its oral absorption.
対処法
Avoid taking oral iron products at the same time as baloxavir; if iron is required, give baloxavir at a different time than the iron dose, or use an alternative antiviral if separation is not feasible.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Baloxavir marboxilとFerrous sulfateの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Ferrous sulfateのその他の相互作用
Baloxavir marboxilのその他の相互作用
よくある質問
Can I take Baloxavir marboxil with Ferrous sulfate?
MediHelp rates the interaction as moderate. Baloxavir marboxil and Ferrous sulfate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Baloxavir can bind to polyvalent cations such as iron in the gut, which may lower its absorption and reduce plasma exposure. This could weaken antiviral effect during influenza treatment or prophylaxis. Supporting data come mainly from animal studies.
How serious is the interaction between Baloxavir marboxil and Ferrous sulfate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid taking oral iron products at the same time as baloxavir; if iron is required, give baloxavir at a different time than the iron dose, or use an alternative antiviral if separation is not feasible.
What other medicines interact with Ferrous sulfate?
MediHelp also lists interactions of Ferrous sulfate with, for example, Ciprofloxacin, Dimercaprol, Acetohydroxamic acid. The full list is on the Ferrous sulfate page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
