相互作用
Calcium carbonate + Ferrous sulfate
重症度: 中等度
Calcium carbonate and Ferrous sulfate: moderate interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Calcium carbonate reduces absorption of oral iron, partly by raising gastric pH and by competing for uptake. This can blunt the response to iron therapy.
この相互作用をわかりやすく説明すると
Calcium carbonate and Ferrous sulfate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Calcium carbonate belongs to Gastrointestinal Tract; Ferrous sulfate belongs to Miscellaneous.
なぜ起こるのか
Higher gastric pH and calcium competition decrease non-heme iron solubility and absorption.
対処法
Separate ferrous sulfate and calcium carbonate by at least 2 hours. Monitor hemoglobin and ferritin.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Calcium carbonateとFerrous sulfateの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Calcium carbonateのその他の相互作用
Ferrous sulfateのその他の相互作用
よくある質問
Can I take Calcium carbonate with Ferrous sulfate?
MediHelp rates the interaction as moderate. Calcium carbonate and Ferrous sulfate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Calcium carbonate reduces absorption of oral iron, partly by raising gastric pH and by competing for uptake. This can blunt the response to iron therapy.
How serious is the interaction between Calcium carbonate and Ferrous sulfate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate ferrous sulfate and calcium carbonate by at least 2 hours. Monitor hemoglobin and ferritin.
What other medicines interact with Calcium carbonate?
MediHelp also lists interactions of Calcium carbonate with, for example, Acalabrutinib, Alendronate, Amlodipine-hydrochlorothiazide-valsartan. The full list is on the Calcium carbonate page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。