相互作用
Ciprofloxacin + Ferrous sulfate
重症度: 重大
Ciprofloxacin and Ferrous sulfate: major interaction.
最終更新日
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概要
Oral iron binds ciprofloxacin in the gut and markedly reduces its absorption. This can lower antibiotic concentrations enough to cause treatment failure and promote resistance.
この相互作用をわかりやすく説明すると
Ciprofloxacin and Ferrous sulfate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Ciprofloxacin belongs to Anti Bacterial; Ferrous sulfate belongs to Miscellaneous.
なぜ起こるのか
Ferrous iron chelates ciprofloxacin in the gastrointestinal tract, forming poorly absorbed complexes.
対処法
Give oral ciprofloxacin at least 2 hours before or 6 hours after iron. Use an alternative if separation is not practical.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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アカウントを作成してPro+トライアルを始めると、CiprofloxacinとFerrous sulfateの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Ciprofloxacinのその他の相互作用
Ferrous sulfateのその他の相互作用
よくある質問
Can I take Ciprofloxacin with Ferrous sulfate?
MediHelp rates the interaction as major. Ciprofloxacin and Ferrous sulfate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Oral iron binds ciprofloxacin in the gut and markedly reduces its absorption. This can lower antibiotic concentrations enough to cause treatment failure and promote resistance.
How serious is the interaction between Ciprofloxacin and Ferrous sulfate?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oral ciprofloxacin at least 2 hours before or 6 hours after iron. Use an alternative if separation is not practical.
What other medicines interact with Ciprofloxacin?
MediHelp also lists interactions of Ciprofloxacin with, for example, Agomelatine, Fezolinetant, Thioridazine. The full list is on the Ciprofloxacin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
