相互作用
Balsalazide + Varicella virus vaccine live
重症度: 重大
Balsalazide and Varicella virus vaccine live: major interaction.
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
概要
Balsalazide is converted to mesalamine, a salicylate, and salicylate use after live varicella vaccination has been linked to Reye's syndrome in children. The risk is largely theoretical given balsalazide's low systemic salicylate exposure, but it is a labeled caution.
この相互作用をわかりやすく説明すると
Balsalazide and Varicella virus vaccine live can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
なぜ起こるのか
Salicylate exposure after live varicella virus vaccination is thought to predispose to Reye's syndrome; the precise mechanism is not established.
対処法
Avoid salicylate-containing products, including balsalazide, for about 6 weeks after vaccination in children and adolescents where possible. If balsalazide is essential, weigh the risks and benefits and counsel caregivers to report vomiting or altered behavior.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、BalsalazideとVaricella virus vaccine liveの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Balsalazideのその他の相互作用
よくある質問
Can I take Balsalazide with Varicella virus vaccine live?
MediHelp rates the interaction as major. Balsalazide and Varicella virus vaccine live can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Balsalazide is converted to mesalamine, a salicylate, and salicylate use after live varicella vaccination has been linked to Reye's syndrome in children. The risk is largely theoretical given balsalazide's low systemic salicylate exposure, but it is a labeled caution.
How serious is the interaction between Balsalazide and Varicella virus vaccine live?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid salicylate-containing products, including balsalazide, for about 6 weeks after vaccination in children and adolescents where possible. If balsalazide is essential, weigh the risks and benefits and counsel caregivers to report vomiting or altered behavior.
What other medicines interact with Balsalazide?
MediHelp also lists interactions of Balsalazide with, for example, Measles mumps rubella and varicella vaccine live, Aceclofenac, Celecoxib. The full list is on the Balsalazide page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
