相互作用
Bcg vaccine live + Everolimus
重症度: 併用禁忌
Bcg vaccine live and Everolimus: contraindicated interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Live BCG vaccine in a patient on everolimus risks disseminated BCG infection because of impaired cell-mediated immunity. The vaccine response may also be reduced.
この相互作用をわかりやすく説明すると
Bcg vaccine live and Everolimus are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
mTOR inhibition-related immunosuppression allows uncontrolled replication of the live attenuated mycobacteria.
対処法
Do not give live BCG vaccine during everolimus therapy. Complete any needed live vaccinations before starting treatment, observing the recommended interval.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Bcg vaccine liveとEverolimusの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を7日間無料でお試し。カード登録不要。
Everolimusのその他の相互作用
よくある質問
Can I take Bcg vaccine live with Everolimus?
MediHelp rates the interaction as contraindicated. Bcg vaccine live and Everolimus are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Live BCG vaccine in a patient on everolimus risks disseminated BCG infection because of impaired cell-mediated immunity. The vaccine response may also be reduced.
How serious is the interaction between Bcg vaccine live and Everolimus?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live BCG vaccine during everolimus therapy. Complete any needed live vaccinations before starting treatment, observing the recommended interval.
What other medicines interact with Everolimus?
MediHelp also lists interactions of Everolimus with, for example, Influenza virus vaccine quadrivalent intranasal, Levoketoconazole, Measles mumps and rubella vaccine live. The full list is on the Everolimus page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
