相互作用
Belladonna and opium + Glycopyrronium
重症度: 中等度
Belladonna and opium and Glycopyrronium: moderate interaction.
最終更新日
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概要
Belladonna and opium suppositories combine an antimuscarinic with an opioid, and with glycopyrronium the anticholinergic and constipating effects add up. Urinary retention, severe constipation and paralytic ileus can result.
この相互作用をわかりやすく説明すると
Belladonna and opium and Glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
なぜ起こるのか
Additive antimuscarinic effects, with opioid-induced reduction of gut and bladder motility compounding them.
対処法
Monitor bowel function and urinary output, and avoid the combination in patients with ileus risk or urinary obstruction.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Belladonna and opiumとGlycopyrroniumの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Glycopyrroniumのその他の相互作用
よくある質問
Can I take Belladonna and opium with Glycopyrronium?
MediHelp rates the interaction as moderate. Belladonna and opium and Glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Belladonna and opium suppositories combine an antimuscarinic with an opioid, and with glycopyrronium the anticholinergic and constipating effects add up. Urinary retention, severe constipation and paralytic ileus can result.
How serious is the interaction between Belladonna and opium and Glycopyrronium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor bowel function and urinary output, and avoid the combination in patients with ileus risk or urinary obstruction.
What other medicines interact with Glycopyrronium?
MediHelp also lists interactions of Glycopyrronium with, for example, Clozapine, Abobotulinumtoxina, Aclidinium. The full list is on the Glycopyrronium page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
