相互作用
Benazepril + Potassium chloride
重症度: 重大
Benazepril and Potassium chloride: major interaction.
最終更新日
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概要
Benazepril reduces renal potassium loss, and added potassium chloride can lead to clinically significant hyperkalemia with arrhythmia risk. Patients with kidney disease or diabetes are at the highest risk.
この相互作用をわかりやすく説明すると
Benazepril and Potassium chloride can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Benazepril belongs to Cardiovascular; Potassium chloride belongs to Gastrointestinal Tract.
なぜ起こるのか
ACE inhibition suppresses aldosterone and decreases potassium excretion, compounding the exogenous potassium load.
対処法
Use potassium chloride only when clearly indicated, with serum potassium and creatinine checks soon after starting and regularly thereafter. Lower or stop the supplement if potassium approaches the upper normal range.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、BenazeprilとPotassium chlorideの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Benazeprilのその他の相互作用
Potassium chlorideのその他の相互作用
よくある質問
Can I take Benazepril with Potassium chloride?
MediHelp rates the interaction as major. Benazepril and Potassium chloride can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Benazepril reduces renal potassium loss, and added potassium chloride can lead to clinically significant hyperkalemia with arrhythmia risk. Patients with kidney disease or diabetes are at the highest risk.
How serious is the interaction between Benazepril and Potassium chloride?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use potassium chloride only when clearly indicated, with serum potassium and creatinine checks soon after starting and regularly thereafter. Lower or stop the supplement if potassium approaches the upper normal range.
What other medicines interact with Benazepril?
MediHelp also lists interactions of Benazepril with, for example, Aliskiren, Sacubitril / valsartan, Sacubitril-valsartan. The full list is on the Benazepril page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
