相互作用
Eplerenone + Potassium chloride
重症度: 併用禁忌
Eplerenone and Potassium chloride: contraindicated interaction.
最終更新日
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概要
Eplerenone limits renal potassium loss, and potassium chloride supplies additional potassium. The combination can cause severe, life-threatening hyperkalemia.
この相互作用をわかりやすく説明すると
Eplerenone and Potassium chloride are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Eplerenone belongs to Cardiovascular; Potassium chloride belongs to Gastrointestinal Tract.
なぜ起こるのか
Additive potassium retention from aldosterone antagonism plus exogenous potassium intake.
対処法
Do not use potassium supplements with eplerenone in labeled hypertension use; otherwise avoid and monitor potassium closely if clinically unavoidable.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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アカウントを作成してPro+トライアルを始めると、EplerenoneとPotassium chlorideの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Eplerenoneのその他の相互作用
Potassium chlorideのその他の相互作用
よくある質問
Can I take Eplerenone with Potassium chloride?
MediHelp rates the interaction as contraindicated. Eplerenone and Potassium chloride are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Eplerenone limits renal potassium loss, and potassium chloride supplies additional potassium. The combination can cause severe, life-threatening hyperkalemia.
How serious is the interaction between Eplerenone and Potassium chloride?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use potassium supplements with eplerenone in labeled hypertension use; otherwise avoid and monitor potassium closely if clinically unavoidable.
What other medicines interact with Eplerenone?
MediHelp also lists interactions of Eplerenone with, for example, Amiloride, Atazanavir, Clarithromycin. The full list is on the Eplerenone page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
