相互作用
Bictegravir + Magnesium citrate
重症度: 中等度
Bictegravir and Magnesium citrate: moderate interaction.
最終更新日
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概要
Magnesium-containing products can bind bictegravir in the gut and lower its absorption. This may reduce antiviral exposure and risk virologic failure or resistance.
この相互作用をわかりやすく説明すると
Bictegravir and Magnesium citrate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
なぜ起こるのか
Chelation of bictegravir by magnesium in the gastrointestinal tract reduces absorption.
対処法
Give bictegravir at least 2 hours before magnesium products under fasting conditions; avoid simultaneous dosing or dosing within 2 hours after the magnesium product.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
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アカウントを作成してPro+トライアルを始めると、BictegravirとMagnesium citrateの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Magnesium citrateのその他の相互作用
よくある質問
Can I take Bictegravir with Magnesium citrate?
MediHelp rates the interaction as moderate. Bictegravir and Magnesium citrate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Magnesium-containing products can bind bictegravir in the gut and lower its absorption. This may reduce antiviral exposure and risk virologic failure or resistance.
How serious is the interaction between Bictegravir and Magnesium citrate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give bictegravir at least 2 hours before magnesium products under fasting conditions; avoid simultaneous dosing or dosing within 2 hours after the magnesium product.
What other medicines interact with Magnesium citrate?
MediHelp also lists interactions of Magnesium citrate with, for example, Ciprofloxacin, Baloxavir marboxil, Cabotegravir. The full list is on the Magnesium citrate page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
